|
KMID : 0939920070390030104
|
|
대한암학회지
2007 Volume.39 No. 3 p.104 ~ p.108
|
|
|
Bone Metastasis from Primary Hepatocellular Carcinoma: Characteristics of Soft Tissue Formation
|
|
Kim Sang-Won
O Jun-Yang
Chun Mi-Son
Wang Hee-Jung
Oh Young-Taek
Cho Sung-Won
Kang Seung-Hee
|
|
|
Abstract
|
|
|
Purpose: To assess the characteristics of bone metastasis from hepatocellular carcinoma and the radiation field arrangement based on imaging studies.
Materials and Methods: Fifty-three patients (84 lesions) with bone metastasis from a primary hepatocellular carcinoma completed palliative radiation therapy. All patients underwent one of following imaging studies prior to the initiation of radiation therapy: a bone scan, computed tomography or magnetic resonance imaging. The median radiation dose was 30 Gy (7∼40 Gy). We evaluated retrospectively the presence of soft tissue formation and the adjustment of the radiation field based on the imaging studies.
Results: Soft tissue formation at the site of bony disease was identified from either a CT/MRI scan (41 lesions) or from a symptomatic palpable mass (5 lesions). The adjustment of the radiation field size based on a bone scan was necessary for 31 of 41 soft tissue forming lesions (75.6%), after a review of the CT/MRI scan. The median survival from the initial indication of a hepatoma diagnosis was 8 months (2 to 71 months), with a 2-year survival rate of 38.6%. The median survival from the detection of a bone metastasis was 5 months (1 to 38 months) and the 1-year overall survival rate was 8.7%.
Conclusion: It was again identified that bone metastasis from a primary hepatocellular carcinoma is accompanied by soft tissue formation. From this finding, an adjustment of the radiation field size based on imaging studies is required. It is advisable to obtain a CT or MRI scan of suspected bone metastasis for better tumor volume coverage prior to the initiation of radiation therapy. (Cancer Res Treat. 2007; 39:104-108)
|
|
|
KEYWORD
|
|
|
Bone metastasis, hepatocellular carcinoma, soft tissue formation, radiation therapy
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|